{"product_id":"proteintech-65053-1-ig","title":"Proteintech, 65053-1-Ig, Anti-Human CD107b \/ LAMP2 (H4B4)","description":"Size: 100ug \/ 500ug\nThe CD107b \/ LAMP2 (65053-1-Ig) by Proteintech is a Monoclonal antibody targeting CD107b \/ LAMP2 in IF\/ICC, FC (Intra) applications with reactivity to human samples\n65053-1-Ig targets CD107b \/ LAMP2 in IF\/ICC, FC (Intra) applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: MCF-7 cells, U-251 cells\nPositive FC (Intra) detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:400-1:1600\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nLAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may play a role in tumor cell metastasis (PMID 9426697).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Human adherent peripheral blood cells Predict reactive species\nFull Name: lysosomal-associated membrane protein 2\nCalculated Molecular Weight: 45 kDa\nGenBank Accession Number: BC002965\nGene Symbol: LAMP2\nGene ID (NCBI): 3920\nENSEMBL Gene ID: ENSG00000005893\nRRID: AB_2881469\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: P13473\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888053768361,"sku":"65053-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65053-1-ig","provider":"Iright","version":"1.0","type":"link"}