{"product_id":"proteintech-65054-1-ig","title":"Proteintech, 65054-1-Ig, Anti-Mouse CD117\/c-Kit (2B8)","description":"Size: 100ug \/ 500ug\nThe CD117\/c-Kit (65054-1-Ig) by Proteintech is a Monoclonal antibody targeting CD117\/c-Kit in FC applications with reactivity to mouse samples\n65054-1-Ig targets CD117\/c-Kit in FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: mouse bone marrow cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early haemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rat \/ IgG2b, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Mouse IL-3-dependent bone marrow mast cells Predict reactive species\nFull Name: kit oncogene\nGenBank Accession Number: BC052457\nGene Symbol: CD117\nGene ID (NCBI): 16590\nRRID: AB_2918362\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: P05532\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888096006313,"sku":"65054-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65054-1-ig","provider":"Iright","version":"1.0","type":"link"}