{"product_id":"proteintech-65155-1-ig","title":"Proteintech, 65155-1-Ig, Anti-Human CD206 (15-2)","description":"Size: 100ug\nThe CD206 (65155-1-Ig) by Proteintech is a Monoclonal antibody targeting CD206 in FC applications with reactivity to human samples\n65155-1-Ig targets CD206 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: GM-CSF treated human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Purified human mannose receptor Predict reactive species\nFull Name: mannose receptor, C type 1\nCalculated Molecular Weight: 166 kDa\nGenBank Accession Number: NM_002438\nGene Symbol: CD206\nGene ID (NCBI): 4360\nRRID: AB_2918437\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Purified by protein-A affinity chromatography\nUNIPROT ID: P22897\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888088338601,"sku":"65155-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65155-1-ig","provider":"Iright","version":"1.0","type":"link"}