{"product_id":"proteintech-65169-1-ig","title":"Proteintech, 65169-1-Ig, Anti-Human CD163 (GHI\/61)","description":"Size: 100ug \/ 500ug\nThe CD163 (65169-1-Ig) by Proteintech is a Monoclonal antibody targeting CD163 in FC applications with reactivity to Human samples\n65169-1-Ig targets CD163 in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD163, also known as M130, is a membrane glycoprotein which belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma\/serum marker for macrophage activity (PMID: 12570164).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Glycoprotein preparation from hairy cell leukemia spleen Predict reactive species\nFull Name: CD163 molecule\nCalculated Molecular Weight: 1156 aa, 125 kDa\nGenBank Accession Number: BC051281\nGene Symbol: CD163\nGene ID (NCBI): 9332\nENSEMBL Gene ID: ENSG00000177575\nRRID: AB_2918446\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q86VB7\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888087945385,"sku":"65169-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65169-1-ig","provider":"Iright","version":"1.0","type":"link"}