{"product_id":"proteintech-65196-1-ig","title":"Proteintech, 65196-1-Ig, Anti-Human CD11c (BU15)","description":"Size: 100ug \/ 500ug\nThe CD11c (65196-1-Ig) by Proteintech is a Monoclonal antibody targeting CD11c in FC applications with reactivity to human samples\n65196-1-Ig targets CD11c in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes\/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α\/β heterodimer with CD18 (integrin β2). CD11c\/CD18 acts as a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Human synovial fluid dendritic cells Predict reactive species\nFull Name: integrin, alpha X (complement component 3 receptor 4 subunit)\nCalculated Molecular Weight: 1169 aa, 129 kDa\nGenBank Accession Number: BC038237\nGene Symbol: CD11c\nGene ID (NCBI): 3687\nENSEMBL Gene ID: ENSG00000140678\nRRID: AB_2918466\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P20702\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888087650473,"sku":"65196-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65196-1-ig","provider":"Iright","version":"1.0","type":"link"}