{"product_id":"proteintech-65247-1-ig","title":"Proteintech, 65247-1-Ig, Anti-Human CD226 (11A8)","description":"Size: 100ug \/ 500ug\nThe CD226 (65247-1-Ig) by Proteintech is a Monoclonal antibody targeting CD226 in FC, ELISA applications with reactivity to Human samples\n65247-1-Ig targets CD226 in FC, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Human NK Cells Predict reactive species\nFull Name: CD226 molecule\nCalculated Molecular Weight: 336 aa, 39 kDa\nGenBank Accession Number: BC074787\nGene Symbol: CD226\nGene ID (NCBI): 10666\nENSEMBL Gene ID: ENSG00000150637\nRRID: AB_2935136\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: Q15762\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888088469673,"sku":"65247-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65247-1-ig","provider":"Iright","version":"1.0","type":"link"}