{"product_id":"proteintech-65270-1-ig","title":"Proteintech, 65270-1-Ig, Anti-Human CD244 (2B4.69)","description":"Size: 100ug \/ 500ug\nThe CD244 (65270-1-Ig) by Proteintech is a Monoclonal antibody targeting CD244 in FC applications with reactivity to Human samples\n65270-1-Ig targets CD244 in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD244, also known as SLAMF4 or 2B4, is a type I transmembrane glycoprotein belonging to the signaling lymphocyte activation molecule (SLAM) family. It consists of an extracellular segment with two immunoglobulin (Ig)-like domains, a transmembrane region, and a cytoplasmic domain containing tyrosine-based motifs (PMID: 9841922; 30546369). CD244 is present on natural killer (NK) cells, γδ T cells, a subset of CD8+ T cells, monocytes, basophils, dendritic cells, and myeloid-derived suppressor cells (MDSCs) (PMID: 30546369). It binds to CD48 with high affinity and transmits stimulatory or inhibitory signals that regulate immune function (PMID: 9841922; 18523281).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: N\/A Predict reactive species\nFull Name: CD244 molecule, natural killer cell receptor 2B4\nGenBank Accession Number: BC028073\nGene Symbol: CD244\nGene ID (NCBI): 51744\nRRID: AB_3084914\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: Q9BZW8\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: 2-8°C.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888088535209,"sku":"65270-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65270-1-ig","provider":"Iright","version":"1.0","type":"link"}