{"product_id":"proteintech-65560-1-mr","title":"Proteintech, 65560-1-MR, Anti-Human HLA-DR (L243) Mouse IgG2a Recombinant Antibody","description":"Size: 100ug\nThe HLA-DR (65560-1-MR) by Proteintech is a Recombinant antibody targeting HLA-DR in FC applications with reactivity to human, monkey, non-human primates samples\n65560-1-MR targets HLA-DR in FC applications and shows reactivity with human, monkey, non-human primates samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHLA-DR is a member of MHC class II molecules encoded by the human leukocyte antigen complex on the region 6p21.31 of chromosome 6. HLA-DR is composed of two non-covalently associated transmembrane glycoproteins (the α and β chains), and is primarily expressed on B lymphocytes, monocytes, dendritic cells and thymic epithelial cells (PMID: 33125816). HLA-DR participates in the antigen presentation to CD4+ or CD8+ T cells and is postulated as a general biomarker of sepsis-induced immunosuppression (PMID: 28199206, 32421903).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, monkey, non-human primates\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: Human lymphoblastoid B-cell line RPMI 8866 Predict reactive species\nFull Name: major histocompatibility complex, class II, DR alpha\nCalculated Molecular Weight: 254 aa, 29 kDa\nGenBank Accession Number: BC032350\nGene Symbol: HLA-DRA\nGene ID (NCBI): 3122\nENSEMBL Gene ID: ENSG00000204287\nRRID: AB_3670314\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P01903\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888550105257,"sku":"65560-1-MR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65560-1-mr","provider":"Iright","version":"1.0","type":"link"}