{"product_id":"proteintech-65567-1-mr","title":"Proteintech, 65567-1-MR, Anti-Human ICAM-1\/CD54 (15.2) Mouse IgG2a Recombinant Antibody","description":"Size: 100ug\nThe ICAM-1\/CD54 (65567-1-MR) by Proteintech is a Recombinant antibody targeting ICAM-1\/CD54 in FC applications with reactivity to human samples\n65567-1-MR targets ICAM-1\/CD54 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: Rheumatoid synovial cells and human monocytes Predict reactive species\nFull Name: intercellular adhesion molecule 1\nCalculated Molecular Weight: 90 kDa\nGenBank Accession Number: BC015969\nGene Symbol: ICAM-1\nGene ID (NCBI): 3383\nENSEMBL Gene ID: ENSG00000090339\nRRID: AB_3670321\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P05362\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888550236329,"sku":"65567-1-MR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65567-1-mr","provider":"Iright","version":"1.0","type":"link"}