{"product_id":"proteintech-65581-1-mr","title":"Proteintech, 65581-1-MR, Anti-Human CD83 (HB15e) Mouse IgG2a Recombinant Antibody","description":"Size: 100ug\nThe CD83 (65581-1-MR) by Proteintech is a Recombinant antibody targeting CD83 in IF\/ICC, FC applications with reactivity to human, non-human primates samples\n65581-1-MR targets CD83 in IF\/ICC, FC applications and shows reactivity with human, non-human primates samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: Raji cells\nPositive FC detected in: Human monocyte-derived mature dendritic cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, non-human primates\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: Human CD83-transfected Cos cells Predict reactive species\nFull Name: CD83 molecule\nCalculated Molecular Weight: 205 aa, 23 kDa\nGenBank Accession Number: BC030830\nGene Symbol: CD83\nGene ID (NCBI): 9308\nENSEMBL Gene ID: ENSG00000112149\nRRID: AB_3670333\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q01151\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888546664617,"sku":"65581-1-MR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-65581-1-mr","provider":"Iright","version":"1.0","type":"link"}