{"product_id":"proteintech-66346-1-ig","title":"Proteintech, 66346-1-Ig, ASNA1 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe ASNA1 (66346-1-Ig) by Proteintech is a Monoclonal antibody targeting ASNA1 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, rat, pig, chicken samples\n66346-1-Ig targets ASNA1 in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse, rat, pig, chicken samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Neuro-2a cells, fetal human brain tissue,  pig brain tissue,  HEK-293 cells,  HeLa cells,  rat brain tissue,  rabbit brain tissue,  mouse brain tissue,  chicken brain tissue\nPositive IHC detected in: human lung cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: HEK-293 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth, increased apoptosis and increased sensitivity to arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition, ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat, pig, chicken\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag7936 Product name: Recombinant human ASNA1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-348 aa of BC002651 Sequence: MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ Predict reactive species\nFull Name: arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)\nCalculated Molecular Weight: 38.7 kDa\nObserved Molecular Weight: 37-41 kDa\nGenBank Accession Number: BC002651\nGene Symbol: ASNA1\nGene ID (NCBI): 439\nRRID: AB_2881726\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: O43681\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888100626601,"sku":"66346-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-66346-1-ig","provider":"Iright","version":"1.0","type":"link"}