{"product_id":"proteintech-68200-1-ig","title":"Proteintech, 68200-1-Ig, CSNK2A1 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe CSNK2A1 (68200-1-Ig) by Proteintech is a Monoclonal antibody targeting CSNK2A1 in WB, IF\/ICC, ELISA applications with reactivity to human, rabbit samples\n68200-1-Ig targets CSNK2A1 in WB, IF\/ICC, IP, ELISA applications and shows reactivity with human, rabbit samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: LNCaP cells, A549 cells,  rabbit heart tissue,  HeLa cells,  HEK-293 cells,  HepG2 cells,  Jurkat cells,  MOLT-4 cells,  K-562 cells,  HL-60 cells\nPositive IF\/ICC detected in: A431 cells, HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:750-1:3000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCSNK2A1(Casein kinase II subunit alpha) is also named as CK2A1 and belongs to the CK2 subfamily. The CSNK2A1 gene contains 8 exons whose sequences comprise bases 102 to 824 of the coding region of the human casein kinase II alpha subunit. Casein kinase II is a ubiquitous protein-serine\/threonine kinase in eukaryotic cells that catalyzes the phosphorylation of many protein substrates and has been regarded as a second-messenger-independent protein kinase. This enzyme is composed of an α subunit (37 to 44kDa) and a β subunit (24 to 28 kDa) and exists as an α2β2 tetramer (PMID:1448100). Casein kinase 2 has been found to be increased at protein level and up-regulated at the level of enzyme activity in the majority of cancers. However, elevated levels of casein kinase 2 are present in certain normal organs such as brain and testes.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, rabbit\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag29062 Product name: Recombinant human CSNK2A1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-391 aa of BC011668 Sequence: MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ Predict reactive species\nFull Name: casein kinase 2, alpha 1 polypeptide\nCalculated Molecular Weight: 45 kDa\nObserved Molecular Weight: 40-45 kDa\nGenBank Accession Number: BC011668\nGene Symbol: CSNK2A1\nGene ID (NCBI): 1457\nRRID: AB_2935289\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: P68400\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888059994281,"sku":"68200-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-68200-1-ig","provider":"Iright","version":"1.0","type":"link"}