{"product_id":"proteintech-68803-2-ig","title":"Proteintech, 68803-2-Ig, FOXP3 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe FOXP3 (68803-2-Ig) by Proteintech is a Monoclonal antibody targeting FOXP3 in WB, IHC, ELISA applications with reactivity to human samples\n68803-2-Ig targets FOXP3 in WB, IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MJ cells\nPositive IHC detected in: human tonsillitis tissue, human appendicitis tissue,  human lymphoma tissue,  human ovary cancer tissue,  human rectal cancer tissue,  MJ cellsNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunohistochemistry (IHC): IHC : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nFOXP3 is a transcription factor belonging to the Forkhead box (FOX) protein family. It contains a forkhead-winged helix domain that acts as a transcriptional activator or repressor. FOXP3 is the master regulator of regulatory T cells (Tregs), a subset of CD4+ T cells with potent suppressive activity. It plays a critical role in maintaining self-tolerance and preventing autoimmune diseases by controlling the development and function of Tregs. The expression of FOXP3 is quite limited, and the cellular taxa present in the tissue are relatively low. Therefore, if you intend to perform Western blotting (WB), it is advisable to enrich the target cells prior to detection.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag23089 Product name: Recombinant human FOXP3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 107-196 aa of BC113401 Sequence: STVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPNPSAPRKDSTLSAVPQSSYPLLAN Predict reactive species\nFull Name: forkhead box P3\nCalculated Molecular Weight: 431 aa, 47 kDa\nObserved Molecular Weight: 47 kDa\nGenBank Accession Number: BC113401\nGene Symbol: FOXP3\nGene ID (NCBI): 50943\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q9BZS1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888062779561,"sku":"68803-2-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-68803-2-ig","provider":"Iright","version":"1.0","type":"link"}