{"product_id":"proteintech-80357-1-rr","title":"Proteintech, 80357-1-RR, Phospho-MKK7 (Ser271\/Thr275) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-MKK7 (Ser271\/Thr275) (80357-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-MKK7 (Ser271\/Thr275) in WB, ELISA applications with reactivity to Human, mouse samples\n80357-1-RR targets Phospho-MKK7 (Ser271\/Thr275) in WB, ELISA applications and shows reactivity with Human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, NIH\/3T3 cells,  Calyculin A treated HeLa cells,  Calyculin A treated NIH\/3T3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDual specificity mitogen-activated protein kinase kinase 7 (MKK7), also known as MEK7 or MAP2K7, is a member of mitogen-activated kinase kinase (MAP2K) subfamily, and a key activator of c-Jun N-terminal kinase (JNK) signaling, a pathway that regulates primarily stress and inflammatory responses. MKK7 activity can be increased by either MKK7-autophosphorylation or phosphorylation of the Ser and Thr residues of the S-X-A-K-T motifs in the Kinase domain by upstream MEKK1, MEKK2, or MLK3.(PMID: 32783966, PMID: 31579105)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: mitogen-activated protein kinase kinase 7\nCalculated Molecular Weight: 47 kDa\nObserved Molecular Weight: 47-52 kDa\nGenBank Accession Number: BC038295\nGene Symbol: MKK7\nGene ID (NCBI): 5609\nRRID: AB_2918891\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: O14733\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888531067049,"sku":"80357-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-80357-1-rr","provider":"Iright","version":"1.0","type":"link"}