{"product_id":"proteintech-82816-4-rr","title":"Proteintech, 82816-4-RR, Phospho-AXL (Tyr779) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-AXL (Tyr779) (82816-4-RR) by Proteintech is a Recombinant antibody targeting Phospho-AXL (Tyr779) in WB, ELISA applications with reactivity to human samples\n82816-4-RR targets Phospho-AXL (Tyr779) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: pervanadate treated A172 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAxl, also known as Ufo or Ark, is a receptor tyrosine kinase of the TAM (Tyro3, Axl and Mer) family. Phospho-AXL (Tyr779) refers to the phosphorylated form of the receptor tyrosine kinase AXL at tyrosine 779 within its intracellular kinase domain. Upon ligand binding (e.g., Gas6 or HGF), AXL dimerizes and undergoes trans-autophosphorylation, generating phospho-Tyr779 that serves as a docking site for the p85 regulatory subunit of PI3K, thereby activating the PI3K\/AKT\/mTOR pathway and promoting cell survival, migration, and invasion. (PMID: 28251492)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: AXL receptor tyrosine kinase\nCalculated Molecular Weight: 894 aa, 98 kDa\nObserved Molecular Weight: 140 kDa\nGenBank Accession Number: BC032229\nGene Symbol: AXL\nGene ID (NCBI): 558\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P30530\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888799731881,"sku":"82816-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-82816-4-rr","provider":"Iright","version":"1.0","type":"link"}