{"product_id":"proteintech-83041-8-rr","title":"Proteintech, 83041-8-RR, Phospho-Histone H2A (Thr120) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-Histone H2A (Thr120) (83041-8-RR) by Proteintech is a Recombinant antibody targeting Phospho-Histone H2A (Thr120) in WB, ELISA, ChIP-qPCR applications with reactivity to human samples\n83041-8-RR targets Phospho-Histone H2A (Thr120) in WB, ELISA, ChIP-qPCR applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Nocodazole and Calyculin A treated HeLa cells\nPositive ChIP-qPCR detected in: Nocodazole (100 ng\/ml) for 16 h HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\nCHIP-QPCR: CHIP-QPCR : 1:10-1:100\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPhospho-Histone H2A (Thr120) refers to the phosphorylation of threonine 120 on histone H2A, a modification that is increasingly recognized for its roles in chromatin organization, gene regulation, and disease development, particularly in oncogenesis and bone remodeling. The phosphorylation is predominantly associated with gene silencing. High levels of H2AT120p correlate with increased cell proliferation, tumor growth, and poor prognosis, underscoring its role as an oncogenic signal.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: histone cluster 1, H2ae\nCalculated Molecular Weight: 14 kDa\nObserved Molecular Weight: 15 kDa\nGenBank Accession Number: BC093836\nGene Symbol: HIST1H2AE\nGene ID (NCBI): 3012\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P04908\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888801861801,"sku":"83041-8-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-83041-8-rr","provider":"Iright","version":"1.0","type":"link"}