{"product_id":"proteintech-83152-5-rr","title":"Proteintech, 83152-5-RR, B7-H3\/CD276 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe B7-H3\/CD276 (83152-5-RR) by Proteintech is a Recombinant antibody targeting B7-H3\/CD276 in WB, ELISA applications with reactivity to Human samples\n83152-5-RR targets B7-H3\/CD276 in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: U2OS cells, HEK-293 cells,  HeLa cells,  LNCaP cells,  human placenta tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nB7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Fusion Protein Predict reactive species\nFull Name: CD276 molecule\nCalculated Molecular Weight: 57 kDa\nObserved Molecular Weight: 95-100 kDa\nGenBank Accession Number: NM_001024736\nGene Symbol: CD276\nGene ID (NCBI): 80381\nRRID: AB_3670847\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q5ZPR3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888590442665,"sku":"83152-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-83152-5-rr","provider":"Iright","version":"1.0","type":"link"}