{"product_id":"proteintech-84165-5-rr","title":"Proteintech, 84165-5-RR, IL-7 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe IL-7 (84165-5-RR) by Proteintech is a Recombinant antibody targeting IL-7 in WB, ELISA applications with reactivity to human samples\n84165-5-RR targets IL-7 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Recombinant protein\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nInterleukin-7 (IL-7) is a non-redundant, pleiotropic cytokine fundamental to the development, homeostasis, and function of the immune system. It is primarily produced by stromal cells in the bone marrow and thymus, as well as by epithelial cells in peripheral lymphoid organs. IL-7 signals through a heterodimeric receptor consisting of the private IL-7 receptor alpha chain (IL-7Rα\/CD127) and the common gamma chain (γc), activating key pathways such as JAK\/STAT, PI3K\/Akt, and MAPK to promote lymphocyte survival, proliferation, and metabolic fitness. Its critical role is underscored by the severe lymphopenia and immunodeficiency observed in both IL-7- and IL-7R-deficient humans and mice.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Product name: HumanKine® recombinant human IL-7 protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species\nFull Name: interleukin 7\nGene Symbol: IL-7\nGene ID (NCBI): 3574\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P13232\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888769487017,"sku":"84165-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-84165-5-rr","provider":"Iright","version":"1.0","type":"link"}