{"product_id":"proteintech-84217-4-rr","title":"Proteintech, 84217-4-RR, KLHDC3 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe KLHDC3 (84217-4-RR) by Proteintech is a Recombinant antibody targeting KLHDC3 in WB, FC (Intra), ELISA applications with reactivity to human, rat samples\n84217-4-RR targets KLHDC3 in WB, FC (Intra), ELISA applications and shows reactivity with human, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: NCI-H1299 cells, PC-3 cells,  HepG2 cells,  K-562 cells,  HEK-293T cells,  rat testis tissue\nPositive FC (Intra) detected in: PC-3 cells, U-251 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe Kelch domain-containing protein 3 (KLHDC3), also designated PEAS, contains 5 Kelch repeats and may be involved in meiotic recombination process. The gene encoding KLHDC3 maps to chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. KLHDC3 protein is mainly expressed in cytoplasm, also found in meiotic chromatin.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag4879 Product name: Recombinant human KLHDC3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-248 aa of BC041793 Sequence: MTPKGPAMCSMPLTSADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNWHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTNSNISRPIVSSHG Predict reactive species\nFull Name: kelch domain containing 3\nCalculated Molecular Weight: 382 aa, 43 kDa\nObserved Molecular Weight: 43 kDa\nGenBank Accession Number: BC041793\nGene Symbol: KLHDC3\nGene ID (NCBI): 116138\nRRID: AB_3671773\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9BQ90\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888774926505,"sku":"84217-4-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-84217-4-rr","provider":"Iright","version":"1.0","type":"link"}