{"product_id":"proteintech-84323-1-rr","title":"Proteintech, 84323-1-RR, RC3H1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe RC3H1 (84323-1-RR) by Proteintech is a Recombinant antibody targeting RC3H1 in WB, ELISA applications with reactivity to human samples\n84323-1-RR targets RC3H1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HepG2 cells, HeLa cells,  HEK-293T cells,  SH-SY5Y cells,  MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRoquin-1 (Rc3h1) is an E3 ubiquitin ligase originally discovered in a mutational screen for genetic factors contributory to systemic lupus erythematosus-like symptoms in mice. A single base pair mutation in the Rc3h1 gene resulted in the manifestation of autoantibody production and sustained immunological inflammation characterized by excessive T follicular helper cell activation and formation of germinal centers. (PMID: 26673963)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: ring finger and CCCH-type zinc finger domains 1\nObserved Molecular Weight: 130-140 kDa\nGenBank Accession Number: NM_172071\nGene Symbol: RC3H1\nGene ID (NCBI): 149041\nRRID: AB_3671865\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q5TC82\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888660402345,"sku":"84323-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-84323-1-rr","provider":"Iright","version":"1.0","type":"link"}