{"product_id":"proteintech-84421-3-rr","title":"Proteintech, 84421-3-RR, ACVRL1 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe ACVRL1 (84421-3-RR) by Proteintech is a Recombinant antibody targeting ACVRL1 in WB, ELISA applications with reactivity to human samples\n84421-3-RR targets ACVRL1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HUVEC cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nACVRL1 (ALK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1 is highly expressed in endothelial cells and has a critical role in the control of blood vessel development and repair (PMID: 8640225). Mutations in the ACVRL1 gene are associated with hemorrhagic telangiectasia type 2.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: FusionProtein Predict reactive species\nFull Name: activin A receptor type II-like 1\nCalculated Molecular Weight: 56 kDa\nObserved Molecular Weight: 63 kDa\nGenBank Accession Number: BC042637\nGene Symbol: ACVRL1\nGene ID (NCBI): 94\nRRID: AB_3671949\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P37023\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888536801449,"sku":"84421-3-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-84421-3-rr","provider":"Iright","version":"1.0","type":"link"}