{"product_id":"proteintech-84798-5-rr","title":"Proteintech, 84798-5-RR, ATIC Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe ATIC (84798-5-RR) by Proteintech is a Recombinant antibody targeting ATIC in WB, IF\/ICC, FC (Intra), ELISA applications with reactivity to human samples\n84798-5-RR targets ATIC in WB, IF\/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, HepG2 cells,  Jurkat cells,  HCT 116 cells,  A549 cells,  MCF-7 cells,  COLO 320 cells\nPositive IF\/ICC detected in: HeLa cells\nPositive FC (Intra) detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\n5-Aminoimidazole-4-carboxamide ribonucleotide formyltransferase\/IMP cyclohydrolase (ATIC, also known as AICAR) is an enzyme that can catalyze the last two reactions in the de novo purine biosynthetic pathway. It has been previously reported to be upregulated and to participate in myeloma and hepatocellular carcinoma progression (PMID: 35251351).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag1052 Product name: Recombinant human ATIC protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 291-592 aa of BC008879 Sequence: DLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH Predict reactive species\nFull Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase\/IMP cyclohydrolase\nCalculated Molecular Weight: 65 kDa\nObserved Molecular Weight: 62 kDa\nGenBank Accession Number: BC008879\nGene Symbol: ATIC\nGene ID (NCBI): 471\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P31939\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888343961769,"sku":"84798-5-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-84798-5-rr","provider":"Iright","version":"1.0","type":"link"}