{"product_id":"proteintech-84976-1-rr","title":"Proteintech, 84976-1-RR, Phospho-TrkA (Tyr496)\/TrkB (Tyr516) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-TrkA (Tyr496)\/TrkB (Tyr516) (84976-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-TrkA (Tyr496)\/TrkB (Tyr516) in WB, ELISA applications with reactivity to human samples\n84976-1-RR targets Phospho-TrkA (Tyr496)\/TrkB (Tyr516) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: pervanadate treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe tyrosine kinase receptor TrkA (or neurotrophin receptor kinase 1, NTRK1) has been predominately studied for its role during the development of the nervous system. In developing neurons, TrkA activation upon binding of its ligands nerve growth factor (NGF) or neurotrophin-3 (NT-3) results in the stimulation of various tyrosine kinase-induced signaling pathways leading to neuronal outgrowth. (PMID: 32957504) This antibody recognizes the phosphorylation of TrkA at site 496, which is the phosphorylation of the TrkA-I(isoform 2) sequence at site 490.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: neurotrophic tyrosine kinase, receptor, type 1\nObserved Molecular Weight: 140 kDa\nGenBank Accession Number: BC062580\nGene Symbol: NTRK1\nGene ID (NCBI): 4914\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P04629\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888805007529,"sku":"84976-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-84976-1-rr","provider":"Iright","version":"1.0","type":"link"}