{"product_id":"proteintech-85168-1-rr","title":"Proteintech, 85168-1-RR, KIR2DL1\/KIR2DL3 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe KIR2DL1\/KIR2DL3 (85168-1-RR) by Proteintech is a Recombinant antibody targeting KIR2DL1\/KIR2DL3 in WB, ELISA applications with reactivity to human samples\n85168-1-RR targets KIR2DL1\/KIR2DL3 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Recombinant protein\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKiller cell immunoglobulin-like receptor 2DL1 (KIR2DL1, also known as CD158A and NKAT1) is an inhibitory receptor of NK cells, with β-arrestin 2 mediated recruitment of the tyrosine phosphatases SHP-1 and SHP-2 to KIR2DL1 and facilitated downstream inhibitory signaling (PMID: 18604210). The effector function of NK cells expressing KIR2DL1 or KIR2DS1 is highly influenced by genetic variability and is calibrated by co-expression of additional NK receptors and cognate HLA-C2 ligands (PMID: 31024561). This antibody can recognize KIR2DL1 and KIR2DL3.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1\nCalculated Molecular Weight: 39 kDa\nObserved Molecular Weight: 45 kDa, 70 kDa\nGenBank Accession Number: BC069344\nGene Symbol: KIR2DL1\nGene ID (NCBI): 3802\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P43626\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888646803625,"sku":"85168-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-85168-1-rr","provider":"Iright","version":"1.0","type":"link"}