{"product_id":"proteintech-85782-2-rr","title":"Proteintech, 85782-2-RR, C4b Alpha Chain\/C4b-B\/C4d-B Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe C4b Alpha Chain\/C4b-B\/C4d-B (85782-2-RR) by Proteintech is a Recombinant antibody targeting C4b Alpha Chain\/C4b-B\/C4d-B in WB, IF\/ICC, ELISA applications with reactivity to human samples\n85782-2-RR targets C4b Alpha Chain\/C4b-B\/C4d-B in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human blood\nPositive IF\/ICC detected in: HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nComplement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single-chain precursor, which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular weights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody raised against 1116-1128aa of human C4b protein can recognize C4b precursor, C4b alpha chain, C4b-B, and C4d-B.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: complement component 4B (Chido blood group)\nCalculated Molecular Weight: 193 kDa\nObserved Molecular Weight: 95 kDa\nGenBank Accession Number: NM_000592\nGene Symbol: C4B\nGene ID (NCBI): 721\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P0C0L5\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888714240169,"sku":"85782-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-85782-2-rr","provider":"Iright","version":"1.0","type":"link"}