{"product_id":"proteintech-86474-3-rr","title":"Proteintech, 86474-3-RR, CHMP6 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe CHMP6 (86474-3-RR) by Proteintech is a Recombinant antibody targeting CHMP6 in WB, ELISA applications with reactivity to human, mouse, rat samples\n86474-3-RR targets CHMP6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A375 cells, A431 cells,  Jurkat cells,  U-937 cells,  mouse testis tissue,  rat testis tissue,  rat lung tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCHMP6 (charged multivesicular body protein 6) is a protein that plays a significant role in the formation of multivesicular bodies (MVBs) within cells. It is a component of the endosomal sorting complex required for transport III (ESCRT-III), which is involved in the sorting and transport of proteins within the cell. CHMP6 has been identified as a novel prognostic biomarker in bladder cancer, where it enhances cell survival and migration by regulating the cell cycle. (PMID: 40630215)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag9357 Product name: Recombinant human CHMP6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-201 aa of BC010108 Sequence: MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVPVKARPRQAELVAAS Predict reactive species\nFull Name: chromatin modifying protein 6\nCalculated Molecular Weight: 201 aa, 23 kDa\nObserved Molecular Weight: 28-30 kDa\nGenBank Accession Number: BC010108\nGene Symbol: CHMP6\nGene ID (NCBI): 79643\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q96FZ7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888726036649,"sku":"86474-3-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-86474-3-rr","provider":"Iright","version":"1.0","type":"link"}