{"product_id":"proteintech-86633-2-rr","title":"Proteintech, 86633-2-RR, CLEC5A Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe CLEC5A (86633-2-RR) by Proteintech is a Recombinant antibody targeting CLEC5A in WB, ELISA applications with reactivity to human samples\n86633-2-RR targets CLEC5A in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: U-251 cells, U-87 MG cells,  THP-1 cells,  K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nC-type lectin domain family 5 member A (CLEC5A, also known as CLECSF5 and MDL1) is a spleen tyrosine kinase (Syk)-coupled receptor abundantly expressed by monocytes, macrophages and neutrophils (PMID: 10449773). It has a pivotal function in activating multiple aspects of innate immunity against bacterial invasion (PMID: 28824166). Both in vitro and in vivo evidence supported that CLEC5A was involved in glioblastoma pathogenesis via regulation of PI3K\/Akt pathway (PMID: 30834619).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: DNA Predict reactive species\nFull Name: C-type lectin domain family 5, member A\nCalculated Molecular Weight: 188 aa, 22 kDa\nObserved Molecular Weight: 22 kDa\nGenBank Accession Number: BC112099\nGene Symbol: CLEC5A\nGene ID (NCBI): 23601\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9NY25\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888606498985,"sku":"86633-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-86633-2-rr","provider":"Iright","version":"1.0","type":"link"}