{"product_id":"proteintech-87015-1-rr","title":"Proteintech, 87015-1-RR, GALR2 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe GALR2 (87015-1-RR) by Proteintech is a Recombinant antibody targeting GALR2 in WB, ELISA applications with reactivity to human, mouse, rat samples\n87015-1-RR targets GALR2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293 cells, SH-SY5Y cells,  C6 cells,  mouse brain tissue,  rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGalanin receptor type 2 (GALR2) is a receptor for galanin, GALP, and the hormone  SPX1 (PMID:24517231). It is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamo-pituitary axis. Activation of the GALR2 may protect the hippocampus from neuronal damage (PMID: 17263796). It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The activity of this receptor is mediated by G proteins that activate the phospholipase C\/protein kinase C pathway (via G(q)) and that inhibits adenylyl cyclase. GALR2 has a calculated molecular weight of 42 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag24154 Product name: Recombinant human GALR2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 287-387 aa of BC074915 Sequence: VNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA Predict reactive species\nFull Name: galanin receptor 2\nCalculated Molecular Weight: 387 aa, 42 kDa\nObserved Molecular Weight: 42 kDa\nGenBank Accession Number: BC074915\nGene Symbol: GALR2\nGene ID (NCBI): 8811\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: O43603\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888754675881,"sku":"87015-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-87015-1-rr","provider":"Iright","version":"1.0","type":"link"}