{"product_id":"proteintech-87413-2-rr","title":"Proteintech, 87413-2-RR, Phospho-Glucocorticoid receptor (Ser211) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-Glucocorticoid receptor (Ser211) (87413-2-RR) by Proteintech is a Recombinant antibody targeting Phospho-Glucocorticoid receptor (Ser211) in WB, ELISA applications with reactivity to human samples\n87413-2-RR targets Phospho-Glucocorticoid receptor (Ser211) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: dexamethasone treated PC-12 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGlucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is a receptor for glucocorticoids, which owns a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Ser211 is located within the hinge region of the GR, which connects the DNA-binding domain and the ligand-binding domain. Phosphorylation at Ser211 is crucial for the receptor's transcriptional activity and nuclear translocation. (PMID: 40362450)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)\nCalculated Molecular Weight: 86 kDa\nObserved Molecular Weight: 95 kDa\nGenBank Accession Number: BC015610\nGene Symbol: Glucocorticoid receptor\nGene ID (NCBI): 2908\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P04150\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888801468585,"sku":"87413-2-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-87413-2-rr","provider":"Iright","version":"1.0","type":"link"}