{"product_id":"proteintech-87485-1-rr","title":"Proteintech, 87485-1-RR, IL-27A p28 Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe IL-27A p28 (87485-1-RR) by Proteintech is a Recombinant antibody targeting IL-27A p28 in WB, ELISA applications with reactivity to rat samples\n87485-1-RR targets IL-27A p28 in WB, ELISA applications and shows reactivity with rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: rat spleen tissue, mouse spleen tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIL-27, as a member of the IL-6\/IL-12 family, is a heterodimeric cytokine composed of two subunits: p28 (IL-27a) and EBI3 (IL-27b). IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg6264 Product name: Recombinant rat IL27A\/IL27 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 29-234 aa of \/ Sequence: FPADPLSLQELRREFTVSLYLARKLLSEVQGYVHSFAESRLPGVNLDLLPVGHHLPNVSLTFQAWRHLSDSDRLCFLATTLRPFPALLGGLETQRTWTSSEREQLWAMRLDLRDLHRHLRFQVLAVGFSCSEEEKEEEEEDEEEEEGKELLLGALGGPNQVSSQVSWPQLLYAYQLLHSLELVLSRAVRDLLLLSLPRRPDSACDP Predict reactive species\nFull Name: interleukin 27\nCalculated Molecular Weight: 27 kDa\nObserved Molecular Weight: 45 kDa\nGenBank Accession Number: \/\nGene Symbol: Il27\nGene ID (NCBI): 365368\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: A6I997\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888769028265,"sku":"87485-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-87485-1-rr","provider":"Iright","version":"1.0","type":"link"}