{"product_id":"proteintech-87619-1-rr","title":"Proteintech, 87619-1-RR, Phospho-MSK1 (Ser376) Recombinant monoclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-MSK1 (Ser376) (87619-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-MSK1 (Ser376) in WB, ELISA applications with reactivity to human samples\n87619-1-RR targets Phospho-MSK1 (Ser376) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Calyculin A treated HeLa cells, PMA treated HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMitogen- and stress-activated kinase 1 (MSK1) is a protein kinase that plays a crucial role in the regulation of gene expression in response to various stimuli, including mitogens, stress, and inflammatory signals. ERK1\/2 or p38 MAPK activate MSK1 by phosphorylating Thr581 and Ser360; this primes the C-terminal domain, which then autophosphorylates Ser376 (and Ser212) to unlock the N-terminal catalytic site. (PMID: 15568999)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: ribosomal protein S6 kinase, 90kDa, polypeptide 5\nCalculated Molecular Weight: 549aa,62 kDa; 802aa,90 kDa\nObserved Molecular Weight: 90 kDa\nGenBank Accession Number: BC017187\nGene Symbol: MSK1\nGene ID (NCBI): 9252\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: O75582\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888803270825,"sku":"87619-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-87619-1-rr","provider":"Iright","version":"1.0","type":"link"}