{"product_id":"proteintech-98061-1-rr","title":"Proteintech, 98061-1-RR, Anti-Human CEACAM1\/3\/6 (CD66a\/c\/d) Rabbit Recombinant Antibody","description":"Size: 100ug\nThe CEACAM1\/3\/6 (CD66a\/c\/d) (98061-1-RR) by Proteintech is a Recombinant antibody targeting CEACAM1\/3\/6 (CD66a\/c\/d) in FC applications with reactivity to human samples\n98061-1-RR targets CEACAM1\/3\/6 (CD66a\/c\/d) in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human peripheral blood leukocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530). This antibody is raised against 35-428 aa of human CEACAM1\/CD66a and can cross-react with CEACAM6\/CD66c and CEACAM3\/CD66d.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)\nCalculated Molecular Weight: 526 aa, 58 kDa\nGenBank Accession Number: BC014473\nGene Symbol: CEACAM1\nGene ID (NCBI): 634\nRRID: AB_3672208\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: P13688\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888547680425,"sku":"98061-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-98061-1-rr","provider":"Iright","version":"1.0","type":"link"}