{"product_id":"proteintech-98281-1-rr","title":"Proteintech, 98281-1-RR, Anti-Human KLRB1\/CD161 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe KLRB1\/CD161 (98281-1-RR) by Proteintech is a Recombinant antibody targeting KLRB1\/CD161 in FC applications with reactivity to human samples\n98281-1-RR targets KLRB1\/CD161 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human peripheral blood leukocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD161, also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor and is expressed on the cell membrane as disulfide-linked homodimer (PMID: 8077657). It is expressed by the majority of NK cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, and is expressed preferentially on adult T cells with a \"memory\" antigenic phenotype (PMID: 8077657; 22566826). Expression of CD161 correlates with the cytotoxic function of CD16+ NK cells, and ligation of CD161 with its ligand LLT1 inhibits NK cell cytotoxicity and cytokine secretion (PMID: 29686665).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant protein Predict reactive species\nFull Name: killer cell lectin-like receptor subfamily B, member 1\nCalculated Molecular Weight: 25 kDa\nGenBank Accession Number: NM_002258.3\nGene Symbol: CD161\nGene ID (NCBI): 3820\nENSEMBL Gene ID: ENSG00000111796\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purfication\nUNIPROT ID: Q12918\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888555643049,"sku":"98281-1-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-98281-1-rr","provider":"Iright","version":"1.0","type":"link"}