{"product_id":"proteintech-biotin-fca98205","title":"Proteintech, Biotin-FcA98205, FcZero-rAb™ Biotin Anti-Human DC-SIGNR\/CD299 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe DC-SIGNR\/CD299 (Biotin-FcA98205) by Proteintech is a Recombinant antibody targeting DC-SIGNR\/CD299 in FC, ELISA applications with reactivity to human samples\nBiotin-FcA98205 targets DC-SIGNR\/CD299 in FC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: Transfected HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDendritic cell-specific intracellular adhesion molecule-3-grabbing non-integrin (DC-SIGN\/CD209) and DC-SIGN related (DC-SIGNR\/CD299\/L-SIGN\/CD209L\/CLEC4M) are trans-membrane C-type lectins that are calcium-dependent carbohydrate-binding proteins, which can act as cell-adhesion and pathogen-recognition receptors (PMID: 18458800). DC-SIGN and DC-SIGNR share 77% amino acid identity (PMID: 10975799; 11226297). DC-SIGN is expressed on subsets of dendritic cells and macrophages while DC-SIGNR is restricted to endothelial cells of the liver, lymph nodes and placenta (PMID: 17509452). DC-SIGNR servers as a receptor for ICAM-3. It recognizes a wide range of evolutionarily divergent pathogens.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Recombinant Protein Predict reactive species\nFull Name: C-type lectin domain family 4, member M\nCalculated Molecular Weight: 45 kDa\nGenBank Accession Number: BC038851\nGene Symbol: DC-SIGNR\/CD299\nGene ID (NCBI): 10332\nConjugate: Biotin\nExcitation\/Emission Maxima Wavelengths: -\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9H2X3\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888623800489,"sku":"Biotin-FcA98205","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-biotin-fca98205","provider":"Iright","version":"1.0","type":"link"}