{"product_id":"proteintech-cl488-85743","title":"Proteintech, CL488-85743, CoraLite® Plus 488-conjugated PELO Recombinant monoclonal antibody","description":"Size: 100ul\nThe PELO (CL488-85743) by Proteintech is a Recombinant antibody targeting PELO in IF\/ICC applications with reactivity to human samples\nCL488-85743 targets PELO in IF\/ICC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: HeLa cells, A549 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe Pelo gene was originally identified in a mutagenesis screen for spermatogenesis-specific genes of Drosophila melanogaster. The PELO is required for the meiotic division during the G2\/M transition, and functions in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs [PMID:12556505]. It may participate in the machinery of protein synthesis or in the regulation of mRNA translation [PMID:9584085].\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag0873 Product name: Recombinant human PELO protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 42-384 aa of BC005889 Sequence: STIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHICLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQRHIHFDVVKCILVASPGFVREQFCDYMFQQAVKTDNKLLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVEKANEAMAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLSQLTGVAAILRFPVPELSDQEGDSSSEE Predict reactive species\nFull Name: pelota homolog (Drosophila)\nCalculated Molecular Weight: 43 kDa\nObserved Molecular Weight: 43-45 kDa\nGenBank Accession Number: BC005889\nGene Symbol: PELO\nGene ID (NCBI): 53918\nConjugate: CoraLite® Plus 488 Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 493 nm \/ 522 nm\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9BRX2\nStorage Buffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.\nStorage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888798322857,"sku":"CL488-85743","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-cl488-85743","provider":"Iright","version":"1.0","type":"link"}