{"product_id":"proteintech-cl555-il6","title":"Proteintech, CL555-IL6, ChromoTek anti-IL6 recombinant VHH, CoraLite® Plus 555","description":"Size: 150ul\nCL555-IL6 is a recombinant CoraLite® Plus 555 conjugated anti IL6 Nanobody (VHH) that targets IL6 in IF and FC applications, showing reactivity with human samples.\n\u003cb\u003eSpecification\u003c\/b\u003e\nApplications: IF, FC\nReactivity: Human\nConjugate: CoraLite® Plus 555\nType: Nanobody\nClass: Recombinant\nHost: Alpaca\nAffinity: 3 nM\nMolecular Weight: 14.1 kDa\nForm: Liquid\nExcitation\/Emission Maxima Wavelengths: 554 nm \/ 570 nm\nRRID: AB_3665391\nStorage Buffer: 10 mM HEPES pH 7.0, 500 mM NaCl, 5 mM EDTA, 0.09% sodium azide\nStorage Condition: Store at -20°C\nShipping: blue ice\nBackground: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888877883561,"sku":"CL555-IL6","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-cl555-il6","provider":"Iright","version":"1.0","type":"link"}