{"product_id":"proteintech-cl555-lt","title":"Proteintech, CL555-lt, ChromoTek anti-LAG3 recombinant VHH, CoraLite® Plus 555","description":"Size: 150ul\nCL555-lt targets LAG3 in FC and IF applications and shows reactivity with Human samples.\n\u003cb\u003eSpecification\u003c\/b\u003e\nApplications: FC, IF\nReactivity: Human\nConjugate: CoraLite® Plus 555\nType: Nanobody\nClass: Recombinant\nHost: Alpaca\nAffinity: Picomolar range, below the assay limit (biolayer interferometry)\nMolecular Weight: 15.141 kDa\nForm: Liquid\nExcitation\/Emission Maxima Wavelengths: 554 nm \/ 570 nm\nRRID: AB_3101917\nStorage Buffer: 500 mM NaCl, 10 mM HEPES pH 7.0, 5 mM EDTA, 0.09% sodium azide\nStorage Condition: Store at -20°C; Shipped at ambient temperature.\nBackground: LAG-3, also known as CD223, is an immune checkpoint molecule that regulates both T-cell activation and homeostasis. LAG-3 is expressed on activated T cells, NK cells, regulatory T cells, and plasmacytoid dendritic cells. It is a CD4-related molecule that binds MHC class II. LAG-3 plays an important role in modulating T cell expansion and function, and blockade of LAG-3 with monoclonal antibodies can augment T cell function. (PMID: 15634887; 21086108; 28783703)","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888878375081,"sku":"CL555-lt","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-cl555-lt","provider":"Iright","version":"1.0","type":"link"}