{"product_id":"proteintech-cl555-msln","title":"Proteintech, CL555-msln, ChromoTek anti-MSLN recombinant VHH, CoraLite® Plus 555","description":"Size: 150ul\nCL555-msln targets MSLN in FC and IF applications and shows reactivity with Human samples.\n\u003cb\u003eSpecification\u003c\/b\u003e\nApplications: FC, IF\nReactivity: Human\nConjugate: CoraLite® Plus 555\nType: Nanobody\nClass: Recombinant\nHost: Alpaca\nAffinity: Picomolar range, below the assay limit (biolayer interferometry)\nMolecular Weight: 15.710 kDa\nForm: Liquid\nExcitation\/Emission Maxima Wavelengths: 554 nm \/ 570 nm\nRRID: AB_3101942\nStorage Buffer: 500 mM NaCl, 10 mM HEPES pH 7.0, 5 mM EDTA, 0.09% sodium azide\nStorage Condition: Store at -20°C\nBackground: Mesothelin (MSLN) is a 40kDa GPI-anchored surface glycoprotein that is expressed on pleural and peritoneal mesothelial cells, but not in other non-neoplastic tissues. The mesothelin gene encodes a 69-71kDa precursor protein that is processed to a 40kDa membrane-bound protein termed mesothelin and a 31kDa shed fragment called megakaryocyte-potentiating factor (MPF) that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues (e.g. mesothelium), and is expressed at high levels in mesotheliomas, as well as ovarian, pancreatic, and lung cancers. Mesothelin may be a new target for immunotherapy (PMID: 20922056, 18691948, 15217923).","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888878538921,"sku":"CL555-msln","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-cl555-msln","provider":"Iright","version":"1.0","type":"link"}