{"product_id":"proteintech-cl647-fca98385","title":"Proteintech, CL647-FcA98385, FcZero-rAb™ CoraLite® Plus 647 Anti-Mouse IL-7Ra\/CD127 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe IL-7Ra\/CD127 (CL647-FcA98385) by Proteintech is a Recombinant antibody targeting IL-7Ra\/CD127 in FC applications with reactivity to mouse samples\nCL647-FcA98385 targets IL-7Ra\/CD127 in FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD127, also known as IL-7R subunit alpha (IL-7Rα), is a type I membrane glycoprotein expressed on thymocytes, B cell precursors, most T cells, and some lymphoid and myeloid cells (PMID: 8415665). IL-7R is a heterodimer composed of CD127 and IL-2Rγ (CD132), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15 (PMID: 8266077; 9862091). IL-7R plays critical roles in lymphocyte development and homeostasis (PMID: 26336149). CD127 can also act as a receptor for thymic stromal lymphopoietin (TSLP) (PMID: 10974032).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg1826 Product name: Recombinant Mouse IL-7Ra\/CD127 protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 21-239 aa of NM_008372.4 Sequence: ESGNAQDGDLEDADADDHSFWCHSQLEVDGSQHLLTCAFNDSDINTANLEFQICGALLRVKCLTLNKLQDIYFIKTSEFLLIGSSNICVKLGQKNLTCKNMAINTIVKAEAPSDLKVVYRKEANDFLVTFNAPHLKKKYLKKVKHDVAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIPHNDYFKGFWSEWSPSSTFETPEPKNQGGWD Predict reactive species\nFull Name: interleukin 7 receptor\nCalculated Molecular Weight: 52 kDa\nGenBank Accession Number: NM_008372.4\nGene Symbol: CD127\nGene ID (NCBI): 16197\nConjugate: CoraLite® Plus 647 Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 654 nm \/ 674 nm\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P16872\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888632418473,"sku":"CL647-FcA98385","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-cl647-fca98385","provider":"Iright","version":"1.0","type":"link"}