{"product_id":"proteintech-pe-fca65613","title":"Proteintech, PE-FcA65613, FcZero-rAb™ PE Anti-Human CD45RO (UCHL1) Rabbit IgG Recombinant Antibody","description":"Size: 100tests\nThe CD45RO (PE-FcA65613) by Proteintech is a Recombinant antibody targeting CD45RO in FC applications with reactivity to human samples\nPE-FcA65613 targets CD45RO in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RO is the shortest CD45 isoform (lacking all three exons) and is expressed by activated and memory T cells, thymocytes, some B cells, and weakly on granulocytes and macrophage (PMID: 27100180; 12414720).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: IL-2 dependent T cell line, CA1 Predict reactive species\nFull Name: protein tyrosine phosphatase, receptor type, C\nGenBank Accession Number: BC014239\nGene Symbol: CD45\nGene ID (NCBI): 5788\nENSEMBL Gene ID: ENSG00000081237\nConjugate: PE Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 496 nm, 565 nm \/ 578 nm\nExcitation Laser: Blue Laser (488 nm)|Green Laser (532 nm)|Yellow-Green Laser (561 nm)\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P08575\nStorage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888621244585,"sku":"PE-FcA65613","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-pe-fca65613","provider":"Iright","version":"1.0","type":"link"}