{"product_id":"proteintech-sf65666-1-tr","title":"Proteintech, SF65666-1-TR, Anti-Mouse CD8a Rat scFv Antibody","description":"Size: 100ug\nThe CD8a (SF65666-1-TR) by Proteintech is a Recombinant antibody targeting CD8a in FC applications with reactivity to mouse samples\nSF65666-1-TR targets CD8a in FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-\/CD8+ T cells (PMID: 1968084).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Type: Rat \/ scFv\nClass: Recombinant\nType: Single-chain variable fragment antibody (scFv)\nImmunogen: N\/A Predict reactive species\nFull Name: CD8 antigen, alpha chain\nGenBank Accession Number: BC030679\nGene Symbol: Cd8a\nGene ID (NCBI): 12525\nConjugate: Unconjugated\nSource: Anti-Mouse CD8a scFv from clone 53-6.7, consisting of VH-GGGGS linker-VL (N- to C-terminus), with a His-C tag at the C-terminus.\nForm: Liquid\nPurification Method: Protein A purification\nStorage Buffer: 50mM HEPES, 150mM NaCl, 5mM EDTA, 0.1% CHAPS, 10% Sucrose and 0.1% Proclin 300, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888702673065,"sku":"SF65666-1-TR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-sf65666-1-tr","provider":"Iright","version":"1.0","type":"link"}