{"product_id":"revvity-3305-001u","title":"Revvity, 3305-001U, GSP Neonatal 17α-OH-progesterone kit","description":"\u003cp\u003eOverview\u003cbr\u003e\nCongenital adrenal hyperplasia (CAH) is a genetic disorder and the most severe form of the disease can lead to a life threatening condition during the first weeks of life. The disease is caused by enzyme defects in steroid biosynthesis, the most frequent types being 21- and 11a-hydroxylase deficiency. These types represent 95% of CAH cases and in both, the 17a-OH progesterone (17OHP), a precursor of cortisol, is increased. The determination of 17OHP is thus a useful screening method for 95% of all CAH cases.\u003cbr\u003e\nGSP Neonatal 17a-OH-progesterone assay:\u003c\/p\u003e\n\n\u003cp\u003eIncubation time 3 h\u003cbr\u003e\nSensitive, robust DELFIA chemistry for confidence in results\u003cbr\u003e\nAll reagents are ready to use\u003cbr\u003e\nContains reagents and plates for 1152 tests (12 plates)\u003c\/p\u003e\n\n\u003cp\u003eThe GSP Neonatal 17a-OH-progesterone assay is based on the competitive binding of europium-labeled 17OHP and 17OHP in the sample to 17OHP-specific antibodies. The fluorescence signal is inversely proportional to the analyte concentration in the sample.\u003cbr\u003e\nAll Revvity neonatal products may not be available in all countries. Application-Newborn Screening\u003cbr\u003e\nBrand-GSP®\u003cbr\u003e\nDetection Modality-Time-Resolved Fluorescence (TRF)\u003cbr\u003e\nDisorders-Congenital Adrenal Hyperplasia (CAH)\u003cbr\u003e\nInstrument Compatibility-GSP\u003cbr\u003e\nQuantity-1152 tests\u003cbr\u003e\nSample Type-Dried blood spots\u003cbr\u003e\nTechnology-DELFIA\u003cbr\u003e\nUnit Size-1 kit\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775215980713,"sku":"3305-001U","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-3305-001u","provider":"Iright","version":"1.0","type":"link"}