{"product_id":"revvity-62amxadc","title":"Revvity, 62AMXADC, HTRF IBMX Phosphodiesterase Inhibitor, 500 µL","description":"\u003cp\u003eOverview\u003cbr\u003e\nPDEs are represented by a large super-family of enzymes whose role is to hydrolyze cAMP into AMP, and cGMP into GMP. It should be emphasized that while not all PDEs lead to the specific hydrolysis of cAMP, the non-selective PDE inhibitor IBMX is often the preferred chemical used in most cAMP accumulation assays.\u003cbr\u003e\nThe use of a Pan-PDE inhibitor ensures that the hydrolysis effect of most PDEs will be inhibited, which in turn guarantees high levels of cAMP accumulation in the cell.\u003cbr\u003e\nHTRF assays offer many advantages over other technologies:\u003c\/p\u003e\n\n\u003cp\u003eHomogeneous add-and-read format\u003cbr\u003e\nNo wash steps\u003cbr\u003e\nLow background\u003cbr\u003e\nStraightforward miniaturization from 96- or 384-well microplates to high density assay formats such as 384-well low volume and 1536-well plates\u003cbr\u003e\nStable signal, providing flexibility in time of readout or size of assays Application-Second Messenger Detection\u003cbr\u003e\nBrand-HTRF\u003cbr\u003e\nDetection Modality-HTRF\u003cbr\u003e\nProduct Group-Buffer\u003cbr\u003e\nShipping Conditions-Shipped Ambient\u003cbr\u003e\nTarget Class-GPCR\u003cbr\u003e\nTechnology-TR-FRET\u003cbr\u003e\nTherapeutic Area-Cardiovascular Infectious Diseases Metabolism\/Diabetes NASH\/Fibrosis Neuroscience Oncology \u0026amp; Inflammation Rare Diseases\u003cbr\u003e\nUnit Size-500 assay points\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775283155113,"sku":"62AMXADC","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-62amxadc","provider":"Iright","version":"1.0","type":"link"}