{"product_id":"revvity-al3169hv","title":"Revvity, AL3169HV, AlphaLISA Human C1q Binding Kit, 100 Assay Points","description":"\u003cp\u003eOverview\u003cbr\u003e\nComplement component 1q, also known as C1q, is a protein complex involved in the complement system. C1q senses antigen\/antibody complexes formed with IgG or IgM and binds to antibody Fc via its globular heads. When this occurs, intramolecular rearrangement of the C1 complex is induced, triggering the activation of C1r and C1s proteases and the sequential cleavage of the circulating complement proteins. This leads to the formation of the Membrane Attack Complex (MAC) and to cell lysis. C1q binding measurements are related to the mechanism of action and Fc effector functions of biologics and therapeutic antibodies and utilized for studies in oncology, autoimmune disease, neurology, and infectious disease.\u003cbr\u003e\nFormats\u003c\/p\u003e\n\n\u003cp\u003eOur 100 assay point kit allows you to run 100 wells in 96-well format, using a 20 µL reaction volume (5 µL of sample).\u003cbr\u003e\nOur 500 assay point kit allows you to run 500 wells in 96-well or 384-well format, using a 20 µL reaction volume (5 µL of sample).\u003cbr\u003e\nOur 5,000 assay point kit allows you to run 5,000 wells in 96-well or 384-well format, using a 20 µL reaction volume (5 µL of sample).\u003c\/p\u003e\n\n\u003cp\u003eFeatures\u003c\/p\u003e\n\n\u003cp\u003eNo-wash steps, no separation steps\u003cbr\u003e\nELISA alternative technology\u003cbr\u003e\nSensitive detection\u003cbr\u003e\nSmall sample volume \u003cbr\u003e\nApplication-Protein-Protein Interaction\u003cbr\u003e\nAutomation Compatible-Yes\u003cbr\u003e\nBrand-AlphaLISA\u003cbr\u003e\nDetection Modality-Alpha\u003cbr\u003e\nProduct Group-Kit\u003cbr\u003e\nSample Volume-5 µL\u003cbr\u003e\nShipping Conditions-Shipped in Blue Ice\u003cbr\u003e\nTarget-C1q\u003cbr\u003e\nTarget Class-Binding Assay\u003cbr\u003e\nTarget Species-Human\u003cbr\u003e\nTechnology-Alpha\u003cbr\u003e\nTherapeutic Area-Autoimmunity Cardiovascular Immuno-oncology Infectious Disease (non-viral) Inflammation Metabolic Neuroscience Oncology Rare Diseases Respiratory Virology\u003cbr\u003e\nUnit Size-100 assay points\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46774535323817,"sku":"AL3169HV","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-al3169hv","provider":"Iright","version":"1.0","type":"link"}