{"product_id":"revvity-cp15g","title":"Revvity, CP15G, PhenoVue ROS-490, Total Oxidative Stress Indicator","description":"\u003cp\u003eOverview\u003cbr\u003e\nReactive oxygen species (ROS) are naturally produced by all living organisms and participate in cell signaling, gene expression and homeostasis. Increasing levels of ROS is associated with aging, as well as with various diseases such as diabetes, pulmonary disorders, inflammatory diseases, and cancer. ROS are also produced by exogenous sources such as UV or heat. Ultimately elevated ROS concentration, which is known as oxidative stress, results in impairment of membrane lipids, proteins, and nucleic acids.\u003cbr\u003e\nROS are reactive molecules which contain oxygen and encompass various entities such as superoxide anion (O2-), hydrogen peroxide (H2O2), hydroxyl radical (•OH), hypochlorous acid (HOCl), peroxynitrite anion (ONOO-), and nitric oxide (NO).\u003cbr\u003e\nPhenoVue ROS Total Oxidative Stress Indicators, encompassing ROS-490, ROS-570 and ROS-670, enable a myriad of applications as well as multiplexing capability to unravel ROS related biological effects.\u003cbr\u003e\nPhenoVue ROS-490, Total Oxidative Stress Indicator is a nonfluorescent cell-permeable probe which emits bright green fluorescence upon reaction with hydroxyl radical, hydrogen peroxide and hypochlorite anion.\u003cbr\u003e\nTypical working concentration: 1-10 µM\u003cbr\u003e\nEquivalent number of microplates:\u003c\/p\u003e\n\n\u003cp\u003e8-24 x 96-well microplates\u003cbr\u003e\n8-24 x 384-well microplates\u003cbr\u003e\n13-40 x 1536-well microplates Color-Green\u003cbr\u003e\nForm-Solid\u003cbr\u003e\nMaximum Emission Wavelength (Em-517 nm\u003cbr\u003e\nMaximum Excitation Wavelength (Ex-498 nm\u003cbr\u003e\nApplication-High Content Imaging Microscopy\u003cbr\u003e\nBrand-PhenoVue™\u003cbr\u003e\nCell Function Indicator-Oxidative stress indicator\u003cbr\u003e\nDetection Modality-Fluorescence\u003cbr\u003e\nFilter-FITC\u003cbr\u003e\nQuantity-1 x 1 mg  (2.362 µmoles)\u003cbr\u003e\nSample Type-Live samples only\u003cbr\u003e\nShipping Conditions-Shipped in Dry Ice\u003cbr\u003e\nStorage Conditions--16 °C or below, protected from light\u003cbr\u003e\nType-Individual reagent\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775377330345,"sku":"CP15G","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-cp15g","provider":"Iright","version":"1.0","type":"link"}