{"product_id":"revvity-nec855250uc","title":"Revvity, NEC855250UC, Hydroxytryptamine Binoxalate (Serotonin Binoxalate), 5-[1- C]-, 250 µCi (9.25 MBq)","description":"\u003cp\u003eOverview\u003cbr\u003e\n250 µCi quantity of 5-Hydroxytryptamine (5-HT) which binds and activates 5-HT (serotonin) receptors. These receptors are a group of GPCR and ligand-gated ion channels found in the peripheral and central nervous system, and are involved in anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation.\u003cbr\u003e\nWe offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.\u003cbr\u003e\nRadiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Concentration-0.1 mCi\/ml\u003cbr\u003e\nMolecular Weight-266.25\u003cbr\u003e\nSpecific Activity-40 - 60 mCi\/mmol (1480 - 2220 MBq\/mmol)\u003cbr\u003e\nCAS Number-85187-10-6\u003cbr\u003e\nApplication-Drug Discovery \u0026amp; Development\u003cbr\u003e\nBrand-NEN Radiochemicals\u003cbr\u003e\nBuffer\/Solvent-Ethanol : water (2:98)\u003cbr\u003e\nDetection Modality-Radiometric\u003cbr\u003e\nLabel Position-Specifically Labeled\u003cbr\u003e\nMolecular Formula-C10H12N20 - C2H2O4\u003cbr\u003e\nPackaging-NENSure vial\u003cbr\u003e\nRadioisotope-14 C\u003cbr\u003e\nReceptor-5-Hydroxytryptamine\u003cbr\u003e\nShipping Information-Shipped Ambient\u003cbr\u003e\nShipping Conditions-Shipped Ambient\u003cbr\u003e\nSpecial Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.\u003cbr\u003e\nStorage Conditions-5°C\u003cbr\u003e\nTherapeutic Area-Cardiovascular CNS \u0026amp; Neurologic\u003cbr\u003e\nUnit Size-250 µCi\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775326441641,"sku":"NEC855250UC","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-nec855250uc","provider":"Iright","version":"1.0","type":"link"}