{"product_id":"revvity-net1232250uc","title":"Revvity, NET1232250UC, Kainic acid, [Isopropenyl- H]-, 250µCi (9.25MBq)","description":"\u003cp\u003eOverview\u003cbr\u003e\n250 µCi quantity of Kainic acid, [Isopropenyl-3H]-, is available for your research. Kainic acid (kainate), labeled with tritium (3H) on the isoprenyl group. Kainic acid is a selective agonist for kainate glutamate receptors, which play a role synaptic plasticity. It is a glutamate analog. Common applications include ligand binding assays.\u003cbr\u003e\nThis product replaces NET875001MC.\u003cbr\u003e\nWe offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.\u003cbr\u003e\nRadiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.\u003cbr\u003e\nReferences for NET1232:\u003c\/p\u003e\n\n\u003cp\u003eHonoré T, Davies SN, Drejer J, Fletcher EJ, Jacobsen P, Lodge D, Nielsen FE. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science (1988) 241 (4866): 701-703. Concentration-1 mCi\/ml\u003cbr\u003e\nMolecular Weight-213.2\u003cbr\u003e\nSpecific Activity-\u0026gt;20 Ci\/mmol (\u0026gt;740 GBq\/mmol)\u003cbr\u003e\nCAS Number-487-79-6\u003cbr\u003e\nApplication-Drug Discovery \u0026amp; Development\u003cbr\u003e\nBrand-NEN Radiochemicals\u003cbr\u003e\nBuffer\/Solvent-Ethanol : water (2:98)\u003cbr\u003e\nDetection Modality-Radiometric\u003cbr\u003e\nLabel Position-Specifically Labeled\u003cbr\u003e\nMolecular Formula-C10H15NO4\u003cbr\u003e\nPackaging-NENSure vial\u003cbr\u003e\nRadioisotope-3 H\u003cbr\u003e\nReceptor-Glutamate\u003cbr\u003e\nShipping Information-Shipped in blue ice\u003cbr\u003e\nShipping Conditions-Shipped in Blue Ice\u003cbr\u003e\nSpecial Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.\u003cbr\u003e\nStorage Conditions-5°C\u003cbr\u003e\nTherapeutic Area-CNS \u0026amp; Neurologic\u003cbr\u003e\nUnit Size-250 µCi\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775329849513,"sku":"NET1232250UC","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-net1232250uc","provider":"Iright","version":"1.0","type":"link"}