{"product_id":"revvity-net858050uc","title":"Revvity, NET858050UC, Oxytocin, [Tyrosyl-3,5- H]-, 50µCi (1.85MBq)","description":"\u003cp\u003eOverview\u003cbr\u003e\nOxytocin is the endogenous ligand for oxytocin receptors. These receptors are a family of GPCRs that are involved in uterine contractions, milk production, stress, anxiety, social memory and recognition, and bonding.\u003cbr\u003e\nWe offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.\u003cbr\u003e\nRadiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.\u003cbr\u003e\nReferences for NET858:\u003c\/p\u003e\n\n\u003cp\u003eBraida, D., Donzelli, A., Martucci, R. et al. Neurohypophyseal hormones manipulation modulate social and anxiety-related behavior in zebrafish. Psychopharmacology (2012) 220: 319.\u003cbr\u003e\nGimpl, G., Fahrenholz, F. Cholesterol as stabilizer of the oxytocin receptor, In Biochimica et Biophysica Acta (BBA) - Biomembranes (2002) 1564 (2): 384-392. Concentration-1 mCi\/ml\u003cbr\u003e\nMolecular Weight-1007.23\u003cbr\u003e\nSpecific Activity-\u0026gt;30 Ci\/mmol (\u0026gt;1110 GBq\/mmol)\u003cbr\u003e\nCAS Number-50-56-6\u003cbr\u003e\nApplication-Drug Discovery \u0026amp; Development\u003cbr\u003e\nBrand-NEN Radiochemicals\u003cbr\u003e\nBuffer\/Solvent-Ethanol : water (8:2)\u003cbr\u003e\nDetection Modality-Radiometric\u003cbr\u003e\nLabel Position-Specifically Labeled\u003cbr\u003e\nMolecular Formula-C43H66N12O12S2\u003cbr\u003e\nPackaging-NENSure vial\u003cbr\u003e\nRadioisotope-3 H\u003cbr\u003e\nReceptor-Oxytocin\u003cbr\u003e\nShipping Information-Shipped in Dry Ice\u003cbr\u003e\nShipping Conditions-Shipped in Dry Ice\u003cbr\u003e\nSpecial Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.\u003cbr\u003e\nStorage Conditions--20°C\u003cbr\u003e\nTherapeutic Area-Gastrointestinal Metabolic Disorders\u003cbr\u003e\nUnit Size-50 µCi\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775365468329,"sku":"NET858050UC","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-net858050uc","provider":"Iright","version":"1.0","type":"link"}