{"product_id":"revvity-net922050uc","title":"Revvity, NET922050UC, Enkephalin, [Tyrosyl-2,6- H(N)]- (2-D-Penicillamine, 5-D-Penicillamine) (DPDPE), 50µCi (1.85MBq)","description":"\u003cp\u003eOverview\u003cbr\u003e\n50µCi quantities of Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine) (DPDPE), are available for your research. DPDPE acts as a selective agonist at delta opioid receptors. These receptors are a subgroup of GPCRs that are potential drug targets for pain and analgesia.\u003cbr\u003e\nWe offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.\u003cbr\u003e\nRadiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.\u003cbr\u003e\nReferences for NET922:\u003c\/p\u003e\n\n\u003cp\u003eBunzow James R.,Saez Carmen,Mortrud Marty,Bouvier Claudia,Williams John T.,Low Malcolm and Grandy David K.(1994), Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type, FEBS Letters, 347.\u003cbr\u003e\nWeber SJ, Greene DL, Sharma SD, Yamamura HI, Kramer TH, Burks TF, Hruby VJ, Hersh LB, Davis TP (1991), Distribution and analgesia of [3H][D-Pen2, D-Pen5]enkephalin and two halogenated analogs after intravenous administration. J Pharmacol Exp Ther 259:1109–1117. Concentration-1 mCi\/ml\u003cbr\u003e\nMolecular Weight-645.7\u003cbr\u003e\nSpecific Activity-20 - 60 Ci\/mmol (740 - 2220 GBq\/mmol)\u003cbr\u003e\nCAS Number-88373-73-3\u003cbr\u003e\nApplication-Drug Discovery \u0026amp; Development\u003cbr\u003e\nBrand-NEN Radiochemicals\u003cbr\u003e\nBuffer\/Solvent-Ethanol containing 10 mM oxidized DTT\u003cbr\u003e\nDetection Modality-Radiometric\u003cbr\u003e\nLabel Position-Specifically Labeled\u003cbr\u003e\nMolecular Formula-C30H39N5O7S\u003cbr\u003e\nPackaging-NENSure vial\u003cbr\u003e\nRadioisotope-3 H\u003cbr\u003e\nReceptor-Opioid\u003cbr\u003e\nShipping Information-Shipped in dry ice\u003cbr\u003e\nShipping Conditions-Shipped in Dry Ice\u003cbr\u003e\nSpecial Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.\u003cbr\u003e\nStorage Conditions--20°C\u003cbr\u003e\nTherapeutic Area-CNS \u0026amp; Neurologic Inflammation Pain\u003cbr\u003e\nUnit Size-50 µCi\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775208804521,"sku":"NET922050UC","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-net922050uc","provider":"Iright","version":"1.0","type":"link"}