{"product_id":"revvity-nev10040","title":"Revvity, NEV10040, IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)","description":"\u003cp\u003eOverview\u003cbr\u003e\nFolate receptors are a family of cell surface receptors that bind the essential vitamin folic acid (folate, vitamin B9). These receptors are upregulated in highly metabolic cells and over-expression of FRA protein is associated with tumor growth, as uptake of folic acid is a necessary part of tumor metabolism.\u003cbr\u003e\nFolate is essential for cellular metabolism and DNA synthesis, methylation, and repair. High metabolic cells such as proliferating cancer cells have increased demand for folate to maintain their accelerated DNA synthesis; thus overexpression of folate receptors (FRs) is a recognized biomarker of many tumors, though tumors can differ in their dependence on folate metabolism. Brand-IVISense\u003cbr\u003e\nFluorescent Agent Type-Targeted\u003cbr\u003e\nImaging Modality-Fluorescence\u003cbr\u003e\nShipping Conditions-Shipped Ambient\u003cbr\u003e\nSpecificity-Folate receptor\u003cbr\u003e\nStorage Conditions-+2 to +8 °C\u003cbr\u003e\nTherapeutic Area-Arthritis Cardiovascular Inflammation Oncology Pulmonary\u003cbr\u003e\nUnit Size-1 vial (10 doses)\u003cbr\u003e\nWave Length-680 nm\u003c\/p\u003e","brand":"Revvity","offers":[{"title":"Default Title","offer_id":46775329587369,"sku":"NEV10040","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/revvity-nev10040","provider":"Iright","version":"1.0","type":"link"}